She made her acting debut with the successful 2010 Tamil period-drama Madrasapattinam, which won her plaudits for her role and launched her acting career. She made her Bollywood debut with Ekk Deewana Tha (2012), starring along side Prateik Babbar.
Amy born on 31 January 1991 in the Isle of Man to Alan and Marguerita Jackson, she has an elder sister Alicia.
In 2009, at the age of 17, Indian film producers spotted her on a model agency website and invited her to audition, which led to her casting as the female lead in the Tamil film Madrasapattinam.
According to the Daily Mail, Jackson Amy "learnt about Bollywood by watching Shilpa Shetty in the reality show Bigg Brother". Later, she was signed by Gautham Menon to play a Malayali Nasrani Christian in Ek Deewana Tha, her Bollywood debut and a Hindi remake of another Tamil-Telugu bilingual film Vinnaithaandi Varuvaayaa (Tamil-2010) and Ye Maaya Chesave (Telugu-2010).
Some sources have reported that Amy is dating Bollywood actor Prateik Babbar, who has moved into her apartment in Bandra, Mumbai However, Prateik denies that they live together,or that they are dating each other.